Endothelin receptor antagonists: Medikamente News - Info Netzwerk Medizin 2000  
Pulmonary arterial hypertension therapy. Info Netzwerk Medizin 2000      
Primary Pulmonary Hypertension (PPH) 
 
 


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KEY PUBLICATION LIST

  1. Abenhaim L, Moride Y, Brenot F et al. Appetite-suppressant drugs and the risk of primary pulmonary hypertension. N Engl J Med (1996) 335:609-16

     
  2. Abraham DJ et al. Increased levels of endothelin-1 and differential enthothelin type A and B receptor expression in scleroderma-associated fibrotic lung disease. AM. J. Pathol (1997) 151:831-841

     
  3. Alpert MA et al. Cardiovascular manifestations of mixed connective tissue disease in adults. Circulation (1983): 68(6):1182-93

     
  4. Archer S, Rich S. Primary pulmonary hypertension: a vascular biology and translational research 'work in progress'. Circulation (2000);102(22):2781-91

     
  5. Borg GA. Psychophysical bases of perceived exertion. Med Sci Sports Exerc (1982);14:377-381

     
  6. Brij S, Peacock AJ. Pulmonary hypertension: its assessment and treatment. Thorax (1999) 54(2):28-32

     
  7. Carratu P et al. ET-1 induces mitogenesis in ovine airway smooth muscle cells via ETA and ETB receptors. Am. J. Physiol (1997) 272 :L1021-1024

     
  8. Channick RN, Simonneau G, Sitbon O et al. Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomized placebo controlled study. Lancet (2000) 358:1119-1123

     
  9. Chen SJ, Chen YF, Meng QC, Durand J, Dicarlo VS, Oparil S. Endothelin-receptor antagonist bosentan prevents and reverses hypoxic pulmonary hypertension in rats. J Appl Physiol (1995);79:2122-2131

     
  10. Clozel M, Breu V, Gray GA et al. Pharmacological characterization of bosentan, a new potent orally active nonpeptide endothelin receptor antagonist. J. Pharmacol. Exp. Ther. (1994) 270:228-235

     
  11. D’Alonzo GE, Barst RJ, Ayres SM et al. Survival in patients with primary pulmonary hypertension: results from a national prospective registry. Ann. Intern. Med. (1991) 115:343-349

     
  12. Ellahham SH, Charlon V et al. Bosentan and the endothelin system in congestive heart failure. Clin Cardiol (2000);23:803-807

     
  13. Gaine SP, Rubin LJ. Primary pulmonary hypertension. Lancet (1998) 352:719-725

     
  14. Galiè N, Grigioni F, Bacchi-Reggiani L, Ussia GP, Parlangeli R, Catanzariti P, et al. Relation of endothelin-1 to survival in patients with primary pulmonary hypertension. Eur J Clin Invest (1996); 26(1):273

     
  15. Galiè N et al. Effects of beraprost sodium, an oral prostacyclin analogue, in patients with pulmonary arterial hypertension: A randomised, double-blind, placebo-controlled trial. JACC (2002) 39(9);1496-502

     
  16. Giaid A, Yanagisawa M, Langleben D et al. Expression of endothelin-1 in the lungs of patients with pulmonary hypertension. N. Engl. J. Med. (1993) 328:1732-1739

     
  17. Gibbs JSR et al. Recommendations on the management of pulmonary hypertension in clinical practice. Heart (Sept 2001);86(1):i1-i13

     
  18. Ishikawa S, Miyauchi T, Ueno H, et al. Influence of pulmonary blood pressure and flow on endothelin-1 production in humans. J Cardiovasc Pharmacol (1995); 26:429-433

     
  19. Kim N, Rubin LJ. Endothelin in health and disease: Endothelin receptor antagonism in the management of pulmonary artery hypertension. J Cardiovasc Pharmacol Therapeut (2002) 7(1):9-19

     
  20. Kleber FX, Petersen S. The peripheral syndrome of heart failure: the overlooked aspects. European Heart Journal (1998) 19(L):L10-L14

     
  21. Koh ET et al. Pulmonary hypertension in systemic sclerosis: an analysis of 17 patients. Br J Rheumatol (1996);35:989-993

     
  22. Levin ER. Endothelins. N Engl J Med (1995) 333:356-363

     
  23. Liu J et al. Unique response of human arteries to endothelin B receptor agonist and antagonist. Clin Sci (Lond) (1996); 90(2): 91-96

     
  24. MacGregor AJ et al. Pulmonary hypertension in systemic sclerosis: risk factors for progression and consequences for survival. Rheumatology (2001); 40;453-59

     
  25. McCulloch KM. et al. EnothelinB receptor-mediated contraction in human pulmonary risistance arteries. Br. J. Pharmacol., (1996) 119:1125-1130

     
  26. Miyamoto S et al. Clinical correlates and prognostic significance of six-minute walk test in patients with primary pulmonary hypertension: Comparison with cardiopulmonary hypertension. Am J Resp and Crit Care Med (2000);161:487-492

     
  27. Nagaya N et al. Oral beraprost sodium improves exercise capacity and ventilatory efficiency in patients with primary or thromboembolic pulmonary hypertension. Heart (2002) 87:340-345

     
  28. Olschewski H et al. Inhaled iloprost for severe pulmonary arterial hypertension. N Engl J Med (2002):347:322-329

     
  29. Park S-H, Saleh D, Giaid A, Michel RP. Increased enothelin-1 in bleomycin-induced pulmonary fibrosis and the effect of an endothelin receptor antagonist. Am. J. Resp. Crit. Care Med. (1997) 156:600-608

     
  30. Rich S, Dantzker DR, Ayres SM et al. Primary pulmonary hypertension: A national prospective study. Ann Intern Med (1987) 107:216-23

     
  31. Rich S (Ed). Primary pulmonary hypertension: Executive summary from the WHO symposium, Evian, France 6-10 Sept 1998

     
  32. Rossi GP et al. Measurement of endothelin: clinical and research use. Ann Clin Biochem (2000) ;37:608-626

     
  33. Roux S, Brue V, Ertel SI, Clozel M. Endothelin antagonism with bosentan: a review of potential applications. J Mol Med (1999);77:364-376

     
  34. Rubin LJ. Primary pulmonary hypertension. N. Engl. J. Med (1997) 336:111-117

     
  35. Rubin LJ, Badesch DB, Barst RJ et al. Bosentan therapy for pulmonary arterial hypertension. N. Engl. J. Med (2002) 346:896-903

     
  36. Saleh D, Furukawa K, Tsao MS, Maghazachi A, Corrin B, Yanagisawa M, et al. Elevated expression of endothelin-1 and endothelin-converting enzyme-1 in idiopathic pulmonary fibrosis: possible involvement of proinflammatory cytokines. Am J Respir Cell Mol Biol (1997); 16:187-193

     
  37. Shi-wen X et al. Fibroblast matrix gene expression and connective tissue remodelling: J Invest Dermatol (2001); 116:417-25

     
  38. Tilton RG, Brock TA, Dixon RAF. Therapeutic potential of endothelin receptor antagonists and nitric oxide donors in pulmonary hypertension. Expert Opin Investig Drugs (2001);10(7):1291-1308

     
  39. Veyssier-Belot C, Cacoub P. Role of endothelial and smooth muscle cells in the physiopathology and treatment management of pulmonary hypertension. Cardiovasc. Res (1999) 44:274-282

     
  40. Wilkins MR, Wharton J. Progress in, and future prospects for, the treatment of primary pulmonary hypertension. Heart (2001) 86;603-604
     
  41. Yanagisawa M et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature (March 1988);332:411-415

     
  42. Yoshida et al. Endothelin-1 augments pressor response to angiotension II infusion in rats. Hypertension (1992); 20:292-97

     
  43. Zouki C et al. Enothelin-1 enhances neutrophil adhesion to human coronary artery endothelial cells: role of ETA receptors and platelet-activating factor. Br J Pharmacol (1999); 127:969-79
     

 


 

www.traxglobal.com

 

 

www.tracleer.com   (USA)

 

 

www.actelion.com

 

 

Pulmonary arterial hypertension therapy: Medikamente News - Info Netzwerk Medizin 2000
 
| Adipositas Therapie | AIDS/HIV | Allergie Therapie | allergisches Asthma | Antibabypille |
| Asthma Therapie | Betablocker Therapie | COPD | Diabetes | Erektile Dysfunktion |
| Evidence based Medicine | Frauenheilkunde | Grippe | Haarausfall Therapie |
| Hausstauballergie | Herzkrankheiten | Herzinsuffizienz Diagnose | Herzinsuffizienz |
| Herzschrittmacher | Highlights Forschung | Humangenetik | Hundehaarallergie |
| Hypertonie | Impotenz Therapie | Impfen | Insektengiftallergie | Insulin Therapie |
| Kardiologie | Katzenhaarallergie | Komplementärmedizin | Krankenhäuser | Krebs |
| Magenleiden | Medikamente | Medizintechnik | Mistel Therapie | Naturheilverfahren |
| Nervenkrankheiten | online Hausarzt | Orthopädie | Osteoporose | Pollenallergie |
| PAH | Pressearchiv | Presseerklärungen | Reisewebsite | Report Medizin | Rheuma |
| Schmerz | Sportmedizin | Tierhaarallergie | Totalendoprothese | Zuckerkrankheit |
| | Medizin 2000 | Impressum | Nutzungsbedingungen | Stichwortsuche |

 

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Endothelin: Medikamente News - Info Netzwerk Medizin 2000
Copyright ©  LaHave Media Services Limited
KEY PUBLICATION LIST. Therapy of pulmonary arterial hypertensin with Bosentan, Tracleer.Medikamente News. Info-Netzwerk Medizin 2000
Endothelin receptor antagonists: Medikamente News - Info Netzwerk Medizin 2000  
Pulmonary arterial hypertension therapy. Info Netzwerk Medizin 2000      
Primary Pulmonary Hypertension (PPH) 
 
 


Startseite
Profieingang mit Passwortschutz
Nutzungsbedingungen
Readaktion Info-Netzwerk Medizin 2000
Kontakt Info-Netzwerk Medizin 2000

 

 


KEY PUBLICATION LIST

  1. Abenhaim L, Moride Y, Brenot F et al. Appetite-suppressant drugs and the risk of primary pulmonary hypertension. N Engl J Med (1996) 335:609-16

     
  2. Abraham DJ et al. Increased levels of endothelin-1 and differential enthothelin type A and B receptor expression in scleroderma-associated fibrotic lung disease. AM. J. Pathol (1997) 151:831-841

     
  3. Alpert MA et al. Cardiovascular manifestations of mixed connective tissue disease in adults. Circulation (1983): 68(6):1182-93

     
  4. Archer S, Rich S. Primary pulmonary hypertension: a vascular biology and translational research 'work in progress'. Circulation (2000);102(22):2781-91

     
  5. Borg GA. Psychophysical bases of perceived exertion. Med Sci Sports Exerc (1982);14:377-381

     
  6. Brij S, Peacock AJ. Pulmonary hypertension: its assessment and treatment. Thorax (1999) 54(2):28-32

     
  7. Carratu P et al. ET-1 induces mitogenesis in ovine airway smooth muscle cells via ETA and ETB receptors. Am. J. Physiol (1997) 272 :L1021-1024

     
  8. Channick RN, Simonneau G, Sitbon O et al. Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomized placebo controlled study. Lancet (2000) 358:1119-1123

     
  9. Chen SJ, Chen YF, Meng QC, Durand J, Dicarlo VS, Oparil S. Endothelin-receptor antagonist bosentan prevents and reverses hypoxic pulmonary hypertension in rats. J Appl Physiol (1995);79:2122-2131

     
  10. Clozel M, Breu V, Gray GA et al. Pharmacological characterization of bosentan, a new potent orally active nonpeptide endothelin receptor antagonist. J. Pharmacol. Exp. Ther. (1994) 270:228-235

     
  11. D’Alonzo GE, Barst RJ, Ayres SM et al. Survival in patients with primary pulmonary hypertension: results from a national prospective registry. Ann. Intern. Med. (1991) 115:343-349

     
  12. Ellahham SH, Charlon V et al. Bosentan and the endothelin system in congestive heart failure. Clin Cardiol (2000);23:803-807

     
  13. Gaine SP, Rubin LJ. Primary pulmonary hypertension. Lancet (1998) 352:719-725

     
  14. Galiè N, Grigioni F, Bacchi-Reggiani L, Ussia GP, Parlangeli R, Catanzariti P, et al. Relation of endothelin-1 to survival in patients with primary pulmonary hypertension. Eur J Clin Invest (1996); 26(1):273

     
  15. Galiè N et al. Effects of beraprost sodium, an oral prostacyclin analogue, in patients with pulmonary arterial hypertension: A randomised, double-blind, placebo-controlled trial. JACC (2002) 39(9);1496-502

     
  16. Giaid A, Yanagisawa M, Langleben D et al. Expression of endothelin-1 in the lungs of patients with pulmonary hypertension. N. Engl. J. Med. (1993) 328:1732-1739

     
  17. Gibbs JSR et al. Recommendations on the management of pulmonary hypertension in clinical practice. Heart (Sept 2001);86(1):i1-i13

     
  18. Ishikawa S, Miyauchi T, Ueno H, et al. Influence of pulmonary blood pressure and flow on endothelin-1 production in humans. J Cardiovasc Pharmacol (1995); 26:429-433

     
  19. Kim N, Rubin LJ. Endothelin in health and disease: Endothelin receptor antagonism in the management of pulmonary artery hypertension. J Cardiovasc Pharmacol Therapeut (2002) 7(1):9-19

     
  20. Kleber FX, Petersen S. The peripheral syndrome of heart failure: the overlooked aspects. European Heart Journal (1998) 19(L):L10-L14

     
  21. Koh ET et al. Pulmonary hypertension in systemic sclerosis: an analysis of 17 patients. Br J Rheumatol (1996);35:989-993

     
  22. Levin ER. Endothelins. N Engl J Med (1995) 333:356-363

     
  23. Liu J et al. Unique response of human arteries to endothelin B receptor agonist and antagonist. Clin Sci (Lond) (1996); 90(2): 91-96

     
  24. MacGregor AJ et al. Pulmonary hypertension in systemic sclerosis: risk factors for progression and consequences for survival. Rheumatology (2001); 40;453-59

     
  25. McCulloch KM. et al. EnothelinB receptor-mediated contraction in human pulmonary risistance arteries. Br. J. Pharmacol., (1996) 119:1125-1130

     
  26. Miyamoto S et al. Clinical correlates and prognostic significance of six-minute walk test in patients with primary pulmonary hypertension: Comparison with cardiopulmonary hypertension. Am J Resp and Crit Care Med (2000);161:487-492

     
  27. Nagaya N et al. Oral beraprost sodium improves exercise capacity and ventilatory efficiency in patients with primary or thromboembolic pulmonary hypertension. Heart (2002) 87:340-345

     
  28. Olschewski H et al. Inhaled iloprost for severe pulmonary arterial hypertension. N Engl J Med (2002):347:322-329

     
  29. Park S-H, Saleh D, Giaid A, Michel RP. Increased enothelin-1 in bleomycin-induced pulmonary fibrosis and the effect of an endothelin receptor antagonist. Am. J. Resp. Crit. Care Med. (1997) 156:600-608

     
  30. Rich S, Dantzker DR, Ayres SM et al. Primary pulmonary hypertension: A national prospective study. Ann Intern Med (1987) 107:216-23

     
  31. Rich S (Ed). Primary pulmonary hypertension: Executive summary from the WHO symposium, Evian, France 6-10 Sept 1998

     
  32. Rossi GP et al. Measurement of endothelin: clinical and research use. Ann Clin Biochem (2000) ;37:608-626

     
  33. Roux S, Brue V, Ertel SI, Clozel M. Endothelin antagonism with bosentan: a review of potential applications. J Mol Med (1999);77:364-376

     
  34. Rubin LJ. Primary pulmonary hypertension. N. Engl. J. Med (1997) 336:111-117

     
  35. Rubin LJ, Badesch DB, Barst RJ et al. Bosentan therapy for pulmonary arterial hypertension. N. Engl. J. Med (2002) 346:896-903

     
  36. Saleh D, Furukawa K, Tsao MS, Maghazachi A, Corrin B, Yanagisawa M, et al. Elevated expression of endothelin-1 and endothelin-converting enzyme-1 in idiopathic pulmonary fibrosis: possible involvement of proinflammatory cytokines. Am J Respir Cell Mol Biol (1997); 16:187-193

     
  37. Shi-wen X et al. Fibroblast matrix gene expression and connective tissue remodelling: J Invest Dermatol (2001); 116:417-25

     
  38. Tilton RG, Brock TA, Dixon RAF. Therapeutic potential of endothelin receptor antagonists and nitric oxide donors in pulmonary hypertension. Expert Opin Investig Drugs (2001);10(7):1291-1308

     
  39. Veyssier-Belot C, Cacoub P. Role of endothelial and smooth muscle cells in the physiopathology and treatment management of pulmonary hypertension. Cardiovasc. Res (1999) 44:274-282

     
  40. Wilkins MR, Wharton J. Progress in, and future prospects for, the treatment of primary pulmonary hypertension. Heart (2001) 86;603-604
     
  41. Yanagisawa M et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature (March 1988);332:411-415

     
  42. Yoshida et al. Endothelin-1 augments pressor response to angiotension II infusion in rats. Hypertension (1992); 20:292-97

     
  43. Zouki C et al. Enothelin-1 enhances neutrophil adhesion to human coronary artery endothelial cells: role of ETA receptors and platelet-activating factor. Br J Pharmacol (1999); 127:969-79
     

 


 

www.traxglobal.com

 

 

www.tracleer.com   (USA)

 

 

www.actelion.com

 

 

Pulmonary arterial hypertension therapy: Medikamente News - Info Netzwerk Medizin 2000
 
| Adipositas Therapie | AIDS/HIV | Allergie Therapie | allergisches Asthma | Antibabypille |
| Asthma Therapie | Betablocker Therapie | COPD | Diabetes | Erektile Dysfunktion |
| Evidence based Medicine | Frauenheilkunde | Grippe | Haarausfall Therapie |
| Hausstauballergie | Herzkrankheiten | Herzinsuffizienz Diagnose | Herzinsuffizienz |
| Herzschrittmacher | Highlights Forschung | Humangenetik | Hundehaarallergie |
| Hypertonie | Impotenz Therapie | Impfen | Insektengiftallergie | Insulin Therapie |
| Kardiologie | Katzenhaarallergie | Komplementärmedizin | Krankenhäuser | Krebs |
| Magenleiden | Medikamente | Medizintechnik | Mistel Therapie | Naturheilverfahren |
| Nervenkrankheiten | online Hausarzt | Orthopädie | Osteoporose | Pollenallergie |
| PAH | Pressearchiv | Presseerklärungen | Reisewebsite | Report Medizin | Rheuma |
| Schmerz | Sportmedizin | Tierhaarallergie | Totalendoprothese | Zuckerkrankheit |
| | Medizin 2000 | Impressum | Nutzungsbedingungen | Stichwortsuche |

 

 e-mail us

Navigationspfeil top

Endothelin: Medikamente News - Info Netzwerk Medizin 2000
Copyright ©  LaHave Media Services Limited